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PubMed Central PMCID: PMC254945
Antagonism of the P2X3 receptor is one of the potential therapeutic strategies for the management of neuropathic pain because P2X3 receptors are predominantly localized on small to medium diameter C- and Aδ-fiber primary afferent neurons
56(4):1739-47
MDA-MB-468 (basal-like) and SkBr3 (HER2-OE) cells in a dose-dependent manner
SCH-442416 290 PubMed Central PMCID: PMC254945SCH 442416 is a selective antagonist of adenosine A2A receptor that binds to human and rat adenosine A2A receptors with Ki of 0. 048 nM and 0. 5 nM, respectively. Product information CAS Number: 316173 57 6 Molecular Weight: 389. 41 Formula: C20H19N7O2 Chemical Name: 2 (furan 2 yl) 7 (3 (4 methoxyphenyl)propyl) 7H pyrazolo[4,3 e][1,2,4]triazolo[1,5 c]pyrimidin 5 amine Smiles: COC1C=CC(CCCN2N=CC3=C2N=C(N)N2N=C(N=C23)C2=CC=CO2)=CC=1 InChiKey:
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