AZ7550 (Compound 28) appeares to offer a broadly similar potency and selectivity profile to the parent compound AZD9291
InChiKey: VJVDLRVFJTVWEO-QFIPXVFZSA-N
5 μM) induces loss of viability and caspase 3/7 activation
Lomerizine has strong reversal effect on MDR in K562/ADM cells by inhibiting P-gp function
N-Acetyl-D-glucosamine ameline AZ7550 (Compound 28) appeares toN Acetyl D Glucosamine (N Acetyl 2 amino 2 deoxy D glucose) is a monosaccharide derivative of glucose. Product information CAS Number: 7512 17 6 Molecular Weight: 221. 21 Formula: C8H15NO6 Chemical Name: N [(5R) 3,4,5,6 tetrahydroxy 1 oxohexan 2 yl]acetamide Smiles: CC(=O)NC(C=O)C(O)C(O)[C@H](O)CO InChiKey: MBLBDJOUHNCFQT QQJWGCFSSA N InChi: InChI=1S C8H15NO6 c1 4(12)9 5(2 10)7(14)8(15)6(13)3 11 h2,5 8,11,13 15H,3H2,1H3,(H,9,12) t5?,6 ,7?,8? m1 s1