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InChi: InChI=1S/C21H18NO4/c1-22-10-16-13(6-7-17(23-2)21(16)24-3)14-5-4-12-8-18-19(26-11-25-18)9-15(12)20(14)22/h4-10H
Chemical Name: 5-nitro-6-[2-(propan-2-yl)benzenesulfonyl]quinolin-8-amine
or ADP-mediated platelet Ca2+ mobilization
6-dihydro-2H-pyran-2-yl]-8-oxononadeca-2
ONO 4817 707enbufen InChi: InChI=1S/C21H18NO4/c1-22-10-16-13(6-7-17(23-2)21(16)24-3)14-5-4-12-8-18-19(26-11-25-18)9-15(12)20(14)22/h4-10HONO 4817 is a potent inhibitor of MMP 2, MMP 3, MMP 7, MMP 9, MMP 12 and MMP 13 with IC50 value of 0. 73 nM, 42 nM, 2500 nM, 1. 1 nM, 2. 1 nM, 0. 45 nM and 1. 1 nM, respectively . Matrix metalloproteinases (MMPs) are zinc dependent endopeptidases that belong to the metzincin superfamily and play an important role in tissue remodeling associated with various physiological or pathological processes such as morphogenesis, angiogenesis, tissue repair,