4-phenyl-5-methyl-1, 2, 3-Thiadiazole ylpropionic acid 29)17-33-15-23(18-11-13-30-14-12-18)25(32-33)20-6-9-22(10-7-20)34-16-21-8-5-19-3-1-2-4-24(19)31-21/h1-15H

29)17-33-15-23(18-11-13-30-14-12-18)25(32-33)20-6-9-22(10-7-20)34-16-21-8-5-19-3-1-2-4-24(19)31-21/h1-15H

Solubility: DMSO : ≥ 31 mg/mL (126

Smiles: CC(C)C1N=C(ON=1)C1CCN(CC1)C1=NC=NC(NC2=CC=C(C=C2F)S(C)(=O)=O)=C1N(=O)=O

InChi: InChI=1S/C25H20N4O5/c1-2-33-24-26-20-9-5-8-19(23(30)31)21(20)29(24)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)22-27-25(32)34-28-22/h3-13H

4-phenyl-5-methyl-1, 2, 3-Thiadiazole ylpropionic acid 29)17-33-15-23(18-11-13-30-14-12-18)25(32-33)20-6-9-22(10-7-20)34-16-21-8-5-19-3-1-2-4-24(19)31-21/h1-15H4 phenyl 5 methyl 1,2,3 Thiadiazole is a CYP2B4 and CYP2E1 inhibitor. Cytochrome P450 (CYP450) enzymes, a superfamily of oxidative catalysts, are important in the biosynthesis and metabolism of a wide range of endogenous molecules and the metabolism of xenobiotics. CYP2B4 can metabolize substituted amines, while CYP2E1 metabolizes various alcohols and halogenated alkenes. In vitro: 4 phenyl 5 methyl 1,2,3 Thiadiazole (PMT) was found to be slightly