Sephin1 Carbonate - PPP1R15A Protein Phosphatase Inhibitor. CAS# 951441-04-6 size:10mg solid 48 µM in HN3 and

Name: Sephin1 Carbonate - PPP1R15A Protein Phosphatase Inhibitor. CAS# 951441-04-6 size:10mg solid 48 µM in HN3 and
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Description

48 µM in HN3 and 5

Collins MT

Derenzini E

2014 Jun 5

Sephin1 Carbonate - PPP1R15A Protein Phosphatase Inhibitor. CAS# 951441-04-6 size:10mg solid 48 µM in HN3 andSephin1 Carbonate, CAS No. 951441 04 6, is a selective inhibitor of a holophosphatase. Sephin1 safely and selectively inhibited a regulatory subunit of protein phosphatase 1 in vivo. Sephin1 selectively bound and inhibited the stress induced PPP1R15A, but not the related and constitutive PPP1R15B, to prolong the benefit of an adaptive phospho signaling pathway, protecting cells from otherwise lethal protein misfolding stress. In vivo, Sephin1 safely

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