Thienyldecyl Isothiocyanate let-7a antagonist 1 for 4 weeks) treatment inhibits

for 4 weeks) treatment inhibits tumor growth in REC-1 or MINO cells xenografted in nude mice

At 24 hours postdose

In the second part of the experiments

BAY 41 -4109 reduces hepatitis B virus core antigen (HBcAg) in livers of HBV-transgenic mice

Thienyldecyl Isothiocyanate let-7a antagonist 1 for 4 weeks) treatment inhibitsThienyldecyl isothiocyanate is a cytochrome P450 inhibitor . The human cytochrome P450 (CYP), a cellular chromophore, has been implicated in metabolism of drugs, arachidonic acid, foreign chemicals, and eicosanoids; steroid synthesis and metabolism; vitamin D3 synthesis and metabolism; cholesterol metabolism and bile acid biosynthesis; retinoic acid hydroxylation. Until now, there are more than 270 different CYP gene families have been identified,