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intermediate duration of action
It is also active on c-Kit and FLT3 with good selectivity on a panel of kinases
InChiKey: UCDKONUHZNTQPY-UHFFFAOYSA-N
pii: S0163-7258(18)30123-2
SNIPER(ABL)-013 28170 intermediate duration of actionSNIPER(ABL) 013, conjugating GNF5 (ABL inhibitor) to Bestatin (IAP ligand) with a linker, induces the reduction of BCR ABL protein with a DC50 of 20 M. Product information Molecular Weight: 839. 90 Formula: C42H52F3N7O8 Chemical Name: (2S) 2 [(2S, 3R) 3 amino 2 hydroxy 4 phenylbutanamido] 4 methyl N (2 {2 [2 (2 {[3 (6 {[4 (trifluoromethoxy)phenyl]amino}pyrimidin 4 yl)phenyl]formamido}ethoxy)ethoxy]ethoxy}ethyl)pentanamide Smiles: