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GSK-LSD1 - LSD1 Inhibitor. CAS# 2102933-95-7 0073 It also promotes tissue regeneration

SKU: 63767157085

4.3
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Description

It also promotes tissue regeneration in mouse models of colon and liver injury

InChi: InChI=1S/C31H28ClN7O2/c1-39(2)16-6-11-28(40)35-21-14-12-20(13-15-21)30(41)36-22-7-5-8-23(17-22)37-31-34-19-26(32)29(38-31)25-18-33-27-10-4-3-9-24(25)27/h3-15

Thiemermann C

Solubility: DMSO up to 20 mM

GSK-LSD1 - LSD1 Inhibitor. CAS# 2102933-95-7 0073 It also promotes tissue regenerationGSK LSD1, CAS No. 2102933 95 7, is a highly potent, specific and irreversible inhibitor of Lysine Specific Demethylase 1 (LSD1). It inhibits LSD1 in biochemical assay with an IC50 ~16 nM, and is > 1000 fold selective over other closely related FAD utilizing enzymes (i. e. LSD2, MAO A, MAO B). GSK LSD1 induces gene expression changes in cancer cell lines (average EC50 < 5 nM) and inhibits cancer cell line growth (average EC50 < 5 nM). Product

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