Pomalidomide-PEG6-butyl iodide 60061 Gimeracil enhances the antitumor activity

Gimeracil enhances the antitumor activity of fluoropyrimidines by competitively and reversibly inhibiting the enzyme dihydropyrimidine dehydrogenase causing decreased degradation of the fluoropyrimidines

Epub 2013 Sep 13

AP1189 reduced cytokine release

PF-3716556

Pomalidomide-PEG6-butyl iodide 60061 Gimeracil enhances the antitumor activityPomalidomide PEG6 butyl iodide is a synthesized E3 ligase ligand linker conjugate that incorporates the Pomalidomide based cereblon ligand and 6 unit PEG linker used in PROTAC technology. Product information CAS Number: 1835705 74 2 Molecular Weight: 761. 60 Formula: C31H44IN3O11 Chemical Name: N [2 (2, 6 dioxopiperidin 3 yl) 1, 3 dioxo 2, 3 dihydro 1H isoindol 4 yl] 24 iodo 3, 6, 9, 12, 15, 18 hexaoxatetracosanamide Smiles: