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are upregulated at late time points (36 and 48 h)
Umbralisib (RP5264
56(21):8931-42
delayed tumor growth in vivo
CE-245677 12288 are upregulated at late timeCE 245677 is a potent reversible inhibitor of Tie2 and TrkA B kinases with a cellular IC50s of 4. 7 and 1 nM. Product information CAS Number: 717899 97 3 Molecular Weight: 513. 38 Formula: C24H22Cl2N6O3 Chemical Name: 3 {5 [4 amino 7 (propan 2 yl) 7H pyrrolo[2,3 d]pyrimidine 5 carbonyl] 2 methoxyphenyl} 1 (2,4 dichlorophenyl)urea Smiles: COC1=CC=C(C=C1NC(=O)NC1=CC=C(Cl)C=C1Cl)C(=O)C1=CN(C(C)C)C2=NC=NC(N)=C12 InChiKey: VFCRSIORGUNNGT UHFFFAOYSA N
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