GBR 12935 Catalog No.:M8659-2 Bucladesine calcium salt acts as

Bucladesine calcium salt acts as a phosphodiesterase (PDE) inhibitor

CAS Number: 1099644-42-4

Maggiore C

1007/s12020-015-0590-1

GBR 12935 Catalog No.:M8659-2 Bucladesine calcium salt acts asGBR 12935 is a piperazine derivative which is a potent and selective dopamine reuptake inhibitor. It was originally developed in its 3H radiolabelled form for the purpose of mapping the distribution of dopaminergic neurons in the brain by selective labelling of dopamine transporter proteins. This has led to potential clinical uses in the diagnosis of Parkinson's disease, although selective radioligands such as Ioflupane (I) are now available for this