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Motesanib also potently inhibits PDGF-induced proliferation and SCF-induced c-kit phosphorylation with IC50 of 207 nM and 37 nM
5 h) and that oral administration will not be a suitable dosing method for in vivo studies
Chemical Name: 2-{ethyl[(5-{[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1
CAS Number: 718612-62-5
1, 4-D-Gulonolactone yl isovanillate Motesanib also potently inhibits PDGF-induced1,4 D Gulonolactone is an endogenous metabolite. Product information CAS Number: 6322 07 2 Molecular Weight: 178. 14 Formula: C6H10O6 Chemical Name: (3R,4S,5S) 5 [(1R) 1,2 dihydroxyethyl] 3,4 dihydroxyoxolan 2 one Smiles: OC[C@@H](O)[C@@H]1OC(=O)[C@H](O)[C@@H]1O InChiKey: SXZYCXMUPBBULW LECHCGJUSA N InChi: InChI=1S C6H10O6 c7 1 2(8)5 3(9)4(10)6(11)12 5 h2 5,7 10H,1H2 t2 ,3+,4 ,5+ m1 s1 Technical Data Appearance: Solid Power Purity: 98% (or refer to
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