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5-24 hours) induces about a five-fold upregulation of Nur77 mRNA expression in hEP2-HEK293/EBNA cells in a dose- and time-dependent
suggesting that VX-745 can inhibit paracrine multiple myeloma (MM) cell growth in the BM milieu and overcome cell adhesion-related drug resistance
CAS Number: 457961-34-1
6 nM) and led to their apoptotic cell death
IKK 16 hydrochloride - CAS# 1186195-62-9 4-al-3β-ol 5-24 hours) induces about aIKK 16 hydrochloride is a selective IB kinase (IKK) inhibitor for IKK2, IKK complex and IKK1 with IC50s of 40 nM, 70 nM and 200 nM, respectively. IKK16 also inhibits leucine rich repeat kinase 2 (LRRK2) with an IC50 of 50 nM. Product information CAS Number: 1186195 62 9 Molecular Weight: 520. 09 Formula: C28H30ClN5OS Chemical Name: 4 (1 benzothiophen 2 yl) N {4 [4 (pyrrolidin 1 yl)piperidine 1 carbonyl]phenyl}pyrimidin 2 amine hydrochloride Smiles:
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