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apoptosis of some cancer cell types
GS 5734-metabolite
Dirhodium-catalyzed enantioselective C-H insertion of N-(2-benzyloxyethyl)-N-(tert-butyl)diazoacetamide and its application for the synthesis of chiral GABOB
TAK-875 has no agonist potency to other members of the FFA receptor family with EC50 >10 μM
PHA-767491 Hydrochloride - CAS# 942425-68-5 noxerine apoptosis of some cancer cellPHA 767491, also known as CAY10572, is a potent, ATP competitive dual cdc7 cdk9 inhibitor (IC50 values are 10 and 34 nM respectively) that prevents initiation of DNA replication. PHA 767491 Suppresses Hepatocarcinoma Synergistically with 5 Fluorouracil. PHA 767491 in combination with 5 FU exhibited much stronger cytotoxicity and induced significant apoptosis manifested by remarkably increased caspase 3 activation and poly(ADP Ribose) polymerase
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