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28)29)7-11-5-13(1-3-17(11)19)22-21(26)23-14-2-4-18-12(6-14)8-16(10-20(18)25)34(30
is a potent and selective Pyruvate kinase M2 (PKM2) activator with EC50 ~38 nM
35)36/h1-8
Although it is clear that felbamate does cause pharmacological inhibition of NMDA receptors
ATB-346 - CAS# 1226895-20-0 Catalog No.:M60414-2S 28)29)7-11-5-13(1-3-17(11)19)22-21(26)23-14-2-4-18-12(6-14)8-16(10-20(18)25)34(30ATB 346, CAS No. 1226895 20 0, is anti inflammatory agent, which is structurally an analogue of naproxen. ABT 346 exhibits anti inflammatory properties similar to naproxen, but with substantially reduced gastrointestinal toxicity. ATB 346 suppressed colonic prostaglandin synthesis and whole blood thromboxane synthesis as effectively as naproxen, but did not induce any gastrointestinal injury. ATB 346 exerts superior chemopreventive effects to those of