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PubMed PMID: 12970382
is a polyether Ca 2+ ionophore
Di Lorenzo G
over a period of 21 days) exhibits robust in vivo efficacy in two Pim kinases driven tumor models
Degarelix acetate - CAS# 934246-14-7 090 PubMed PMID: 12970382Degarelix acetate, CAS No. 934246 14 7, also known as FE 200486 and ASP 3550, is a long acting, synthetic peptide with gonadotrophin releasing hormone (GnRH) antagonistic properties. Degarelix targets and blocks GnRH receptors located on the surfaces of gonadotroph cells in the anterior pituitary, thereby reducing secretion of luteinizing hormone (LH) by pituitary gonadotroph cells and so decreasing testosterone production by interstitial (Leydig)
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